Disclaimer: Synergistiq Wellness encourages consults in order to gain the best knowledge in the use of peptides. When you order a peptide, you will receive basic instructions on general use. A multi-use bacteriostatic water vial (30 mL) and 1 pack of 10 insulin syringes per peptide vial will be included complimentary.
NOTE: It is important to consult a qualified healthcare provider before beginning any peptide therapy to determine the appropriate use and dosage for your specific needs, as regulations and administration methods can vary.ย
In the event peptides are on backorder due to manufacturing and popularity, we will notify you and we thank you for your patience. Please include your email and phone number when placing orders to enhance proper communication and tracking info when requested.
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SS-31 (also known as elamipretide) is a mitochondria-targeting peptide that is being researched for its ability to improve cellular energy production and protect cells from damage. Its benefits stem from its unique mechanism of action at the inner mitochondrial membrane,
Mechanisms of Action:
SS-31 works primarily by binding with high affinity to cardiolipin, a key phospholipid found exclusively in the inner mitochondrial membrane. This interaction provides several benefits.
- Antioxidant Effects: It acts as a potent, mitochondria-specific antioxidant, directly scavenging reactive oxygen species (ROS) and preventing lipid peroxidation and oxidative damage.
- Enhanced Energy Production: By stabilizing cardiolipin, it optimizes the organization of the electron transport chain (ETC) into super-complexes, leading to more efficient ATP (cellular energy) synthesis and reduced electron leakage.
- Mitochondrial Protection: It helps maintain mitochondrial membrane integrity, prevents mitochondrial swelling, and inhibits the opening of the mitochondrial permeability transition pore (mPTP), a key event in cell death.
- Cardiovascular Health: Preclinical studies show SS-31 may protect cardiac cells from ischemia-reperfusion injury, improve heart function in heart failure models, and reduce damage after myocardial infarction.
- Renal Protection: It has demonstrated protective effects against various kidney diseases, including acute kidney injury (AKI), chronic kidney disease (CKD), and diabetic nephropathy, by reducing inflammation, fibrosis, and oxidative stress.
- Neuroprotection: SS-31 shows promise in animal models for protecting against neurodegenerative conditions like Alzheimer's and Parkinson's diseases, traumatic brain injury (TBI), and age-related cognitive decline by enhancing neuronal mitochondrial function.
- Muscle Function and Aging: In aged mice, SS-31 treatment reversed age-related declines in muscle function, improved exercise tolerance, and promoted muscle regeneration, suggesting potential anti-aging and performance enhancement applications.
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Ophthalmic Health: Studies suggest it may help protect retinal cells from damage, offering a potential therapeutic strategy for conditions like glaucoma and age-related macular degeneration.